WD Loughman

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WILLIAM D. LOUGHMAN, PhD, ABMG
393 Gravatt Dr., Berkeley, CA 94705
voice: (510) 841-7428   Internet: wdlkhl@attglobal.net

Publications and Presentations
31 December 2002


Peer-reviewed:

  1. Hairr, G.M. and W.D. Loughman: Health Physics Aspects of Irradiation of Large Animals and Human Beings with Curie Quantities of Internally Administered Isotopes. Health Physics 9:987-992 (1963).

  2. Winchell, H.S., M. Pollycove, W.D. Loughman, and J.H. Lawrence: A Method for Maintenance of Curie Quantities of 90Y-DTPA in the Human Body for Defined Time Periods: Technique and Dosimetry. J. Nucl. Med. 5:16-26 (1964).

  3. Winchell, H.S., M. Pollycove, W.D. Loughman, and J.H. Lawrence: Autologous Bone Marrow Transplantation Studies in Dogs Irradiated by 90Y-DTPA. Blood 23:44-52 (1964).

  4. Winchell, H.S., M. Pollycove, W.D. Loughman, V. Richards, L. Kim, and J.H. Lawrence: Homotransplantation Studies in Dogs Following Selective Lymphatic Ablation. Proceedings of the Xth Congress of the International Society of Hematology, Stockholm (1964).

  5. Winchell, H.S., M. Pollycove, W.D. Loughman, V. Richards, L. Kim and J.H. Lawrence: Homotransplantation Studies in Dogs Following Selective Radioisiotopic Lymphatic Ablation. J. Nucl. Med. 7:416-423 (1966).

  6. Curtis, S.B., J.M. Feola, W.D. Loughman, M.R. Raju, C. Richman, S. Richman, and J.H. Lawrence: Present Prospects of Pion Radiotherapy. Third International Conference on Radiation Biology. Proceedings. Cortina d'Ampezzo, Italy, 27 June - 2 July 1966.

  7. Loughman, W.D.: (no title: letter concerning I-131 therapy for thyrotoxicosis). New Engl. J. Med. 276:642-643 (1967).

  8. Loughman, W.D., T.W. Sargent and D.M. Israelstam: Leukocytes of Humans Exposed to Lysergic Acid Diethylamide: Lack of Chromosomal Damage. Science 158:508-510 (1967).

  9. Loughman, W.D.: RBE of Pion Beams in the Bragg Peak Region Determined with Polyploidy Induction in Mammalian Cells Irradiated in vivo. Rad. Res. 34:56-59 (1968); Errata in: Rad. Res. 36:646 (1968).

  10. Loughman, W.D. and T.W. Sargent: Chromosome Damage by LSD. Science 159:1493 (1968).

  11. Loughman, W.D., F.L. Frye, and T.B. Condon: XY/XXY Bone Marrow Mosaicism in Three Male Tricolor Cats. Am. J. Vet. Res. 31:307-314 (1970).

  12. Loughman, W.D., F.L. Frye, and E.S. Herald: The Chromosomes of a Male Manatee, Trichechus inunguis. International Zoo Yearbook 10:151-152 (1970).

  13. Dishotsky, N.I., W.D. Loughman, R.E. Mogar and W.R. Lipscomb: LSD and Genetic Damage. Science 172:431-440 (1971).

  14. Loughman, W.D. and F.L. Frye: The Chromosomes of a Female Giant Anteater, Myrmecophaga tridactyla. J. Zoo Animal Med. 5(2): 23-25 (1974).

  15. Loughman, W.D. and F.L. Frye: XY/XYY Bone Marrow Karyotype in a Male Siamese Crossbred Cat. Vet. Med./Small Animal Clinician 69:1007-1011 (1974).

  16. Fawwaz, R.A., F. Frye, W. Loughman and W. Hemphill: Survival of Skin Homografts in Dogs Injected with 109Pd-protoporphyrin. J. Nucl. Med. 15: 997-1002 (1974).

  17. Frye, F.L., J.D. Carney, and W.D. Loughman: Lepromatous Leprosy in a Cat. Vet. Med./Small Animal Clinician 69:1272-1274 (1974).

  18. Loughman, W.D.: Cytogenetics and Fanconi's Anemia: Experimental and Other Studies of a Family. Ph.D. Dissertation , University of California, Berkeley (June 1973). Lawrence Berkeley Laboratory Report LBL-2001, May 1973.

  19. Curry, C., U. Francke , W. Loughman, B.D. Hall, M.S. Golbus, and C.J. Epstein: Partial Trisomy for the Tip of the Long Arm of Chromosome 5 (5q34->qterm): Delineation of the Clinical Syndrome. Clin Res. 25:175A (1977).

  20. Golbus, M.S., W.D. Loughman, C.J. Epstein, G.N. Halbasch, J.D. Stevens, and B.D. Hall: Prenatal Diagnosis in 3000 Amniocenteses. N. Engl. J. Med. 300:157-163 (1979).

  21. Brown, P.A. and W.D. Loughman: Visible Light Observations on the Kinetochore of the Indian Muntjac, Muntiacus muntjac, Z. Cytogen. Cell. Gen. 27:123-128 (1980).

  22. Mitchell, J.A., W.D. Lougman, and C.J. Epstein: GENFILES - An Information Network in Medical Genetics. In: Proceedings of the Sixth Illinois Conference on Medical Information Systems. Urbana, Illinois (1980).

  23. Loughman, W.D.: MOVIT. Dr. Dobb's Journal of Computer Calisthenics and Orthodontia 5:37 (1980).

  24. Loughman, W.D., J.A. Mitchell, D.C. Mosher, and C.J. Epstein: GENFILES: A Computerized Medical Genetics Information Network. I. An Overview. Am. J. Med. Gen. 7:243-250 (1980).

  25. Mitchell, J.A., W.D. Loughman, and C.J. Epstein: GENFILES: A Computerized Medical Genetics Information Network. II. MEDGEN: The Clinical Genetics System. Am. J. Med. Gen. 7:251-266 (1980).

  26. Mitchell, J.A., C.J. Epstein, and W.D. Loughman: GENFILES: A Computerized Medical Genetics Information Network. III. CHROMO: The Cytogenetics Database. Am. J. Med. Gen. 7:267-278 (1980).

  27. Mitchell, J.A., S. Packman, W.D. Loughman, R.M. Fineman, E. Zachai, S.R. Patil, B. Emanuel, J.A. Bartley, and J.W. Hanson: Deletions of Different Segments of the Long Arm of Chromosome 4. Am. J. Human Genetics 8:73-89 (1981).

  28. Loughman, W.D. and C. Messineo: Sequential Analysis Using BASIC. ACCEPTED - Byte magazine (1981).

  29. Ward, P., S. Packman, W. Loughman, A. McMahon, and A. Ablin: Location of the Retinoblastoma Susceptibility Gene(s). ACCEPTED - Cancer Genetics and Cytogenetics (1981).

  30. Mitchell, J.A., W.D. Loughman, and C.J. Epstein: A Medical Genetics Information System. J. Clin. Computing 11(1):1-43 (1982).

  31. Ward, P., S. Packman, W. Loughman, M. Sparkes, R. Sparkes, A. McMahon, T. Gregory, and A. Ablin: Location of the Retinoblastoma Susceptibility Gene(s) and the Human Esterase D Locus. J. Med. Gen. 21(2):92-95 (1984).


Abstracts:

  1. Pollycove, M., H.S. Winchell, V. Richards, W.D. Loughman and J.H. Lawrence: Homologous Bone Marrow and Kidney Transplantation Using 90Y-DTPA. (Abstract). Clin. Res. 10:112 (1962).

  2. Winchell, H.S., M. Pollycove, W.D. Loughman and J.H. Lawrence: Internally Administered 90Y-DTPA in Preparation for Homografting of Tissues in Dogs and Man. (Abstract). J. Nucl. Med. 4:187 (1963).

  3. Pollycove, M., H.S. Winchell, W.D. Loughman, and J.H. Lawrence: Treatment of Acute Lymphoblastic Leukemia in Relapse Using 90Y-DTPA Irradiation. (Abstract). J. Clin. Invest. 42:965 (1963).

  4. Winchell, H.S., M. Pollycove, W.D. Loughman and J.H. Lawrence: Homologous Tissue Transplantation Studies in Dogs Following Selective Lymphatic Irradiation. (Abstract). Clin. Res. 12:87 (1964).

  5. Loughman, W.D., J.M. Feola, M.R. Raju, H.S. Winchell, and J.H. Lawrence: RBE of Pion Beams for Mammalian Cells in vivo. (Abstract). Clin. Res. 15:110 (1967).

  6. Loughman, W.D.: RBE of Negative Pion Beams in the Bragg Peak Region. (Abstract). J. Nucl. Med. 8:341(1967).

  7. Loughman, W. and D.C. Mosher: A New Cytogenetics/ Medical Genetics Computerized Data Management System. (Abstract). Am. J. Hum. Gen. 30: 87A (1978).

  8. Loughman, W.D.: Fanconi's Anemia: Intra-Family Variation in Radiothymidine Labelling Patterns of Cultured Lymphocyte Metaphases. (Abstract). Genetics 74(Suppl.): 163 (1973).

  9. Levenson, R.M., M. Klagsbrun, M.S. Golbus, W.D. Loughman, and C.J. Epstein: Stimulation of Growth of Amniotic Fluid Cells by Cartilage Growth Factor. (Abstract). Clin Res. 26(5):736A (1978).

  10. Loughman, W.D., J.A. Mitchell, S. Packman, S. Grizzard, and A. McWhinney: Interstitial Deletion of 4q [46,XX, del(4)(q21.3,q26?)] in an Infant with Congenital Anomalies. (Abstract). Am. J. Hum. Gen. 31:77A (1979).

  11. Ward, P., S. Packman, W. Loughman, A. McMahon, and A. Ablin: Location of the Retinoblastoma Susceptibility Gene(s). (Abstract). Am. J. Hum. Gen. 32:93A (1980).


Reports:

  1. Loughman, W.D., H.S. Winchell, and M. Pollycove: Studies on Chromosomes by Means of Short-term Lymphocyte Culture. p. 165 UCRL Report No. 11387, Semi-Annual Report, Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (Spring 1964).

  2. Loughman, W.D.: The Karyotype of the Dog (Canis familiaris) Obtained from Cultures of Peripheral Blood Lymphocytes. UCRL Report No. 11786, Lawrence Radiation Laboratory, Berkeley, California. (M.S. Thesis) (November 1964).

  3. Loughman, W.D.: Mouse Peripheral Blood White Cell Culture. Mammalian Chromosome Newsletter No. 18, pp. 145-146 (November 1965).

  4. Loughman, W.D.: Technical Notes on Short-term Culture of Canine Peripheral Blood Leukocytes for Karyotyping. Mammalian Chromosome Newsletter No. 18, p. 154 (November 1965).

  5. Loughman, W.D., H.S. Winch ell, H. Aceto, C. Richman, M.R. Raju and J.H. Lawrence: Differential Cytologic Effects of Negative Pion Beams in Plateau and "Star" Regions. Preliminary Report. pp. 100-102 UCRL Report No. 16246, Semi-Annual Report, Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (Spring 1965).

  6. Loughman, W.D., H.S. Winchell, M .R. Raju, and J.H. Lawrence: A Significant Difference in Mammalian Cell Polyploidy Induction Between Plateau and "Star" Regions of a Negative Pion Beam. pp. 11-13 UCRL Report No. 16898, Semi-Annual Report, Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (Fall 1966).

  7. Loughman, W.D.: Chromosome Aberrations in Polycythemia Vera and Related Myeloproliferative Disorders. p. 121 (Proceedings) Meetings of the Advisory Committee for Biology and Medicine, United States Atomic Energy Commission, Lawrence Radiation Laboratory, Berkeley, California (March 1967).

  8. Loughman, W.D.: RBE of Negative Pions in the Bragg-Peak Region. pp. 130-131 (Proceedings) Meetings of the Advisory Committee for Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (March 1967).

  9. Loughman, W.D.: The RBE of Negative Pion Beams. pp. 266-272 UCRL Report No. 17457, Semi-Annual Report, Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (March 1967).

  10. Feola, J.M., W.D. Loughman and C. Richman: Pion Radiobiology. pp. 368-381, Proceedings of the 1st International Symposium on the Biological Interpretation of Dose from Accelerator-Produced Radiation, Lawrence Radiation Laboratory, Berkeley, California (March 13-16, 1967).

  11. Loughman, W.D.: A Karyotype Analysis of the M3-1 Tissue Culture Line of Chinese Hamster Fibroblasts. pp. 48-49 UCRL Report No. 18066, Semi-Annual Report, Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (Fall 1967).

  12. Loughman, W.D., and H.S. Winchell: A Case of Atypical Myeloid Metaplasia with Myeloid C-Trisomy. pp. 19-24 UCRL Report No. 19240, Semi-Annual Report, Biology and Medicine, Lawrence Radiation Laboratory, Berkeley, California (Spring 1970).


Other:

  1. Anonymous (W.D. Loughman): Review of Conel, J.L., Life as Revealed by The Microscope. AAAS Science Books 6:220-221 (1970).

  2. Anonymous (W.D. Loughman): Review of Burton, A. L., Cinematographic Techniques in Biology and Medicine. AAAS Science Books 8:81 (1972).

  3. Loughman, W.D.: Review of Noren, C., Photography: How to Improve Your Technique. AAAS Science Books 10:154-155 (1974).

  4. Loughman, W.D.: Review of Borek, E., The Sculpture of Life. AAAS Science Books 10:35-36 (1974).

  5. Loughman, W.D.: Review of Zakia, R.D., Perception and Photography. AAAS Science Books 11:29 (1975).

  6. Loughman, W.D.: Review of Kettlekamp, L., Tricks of Eye and Mind: The Story of Optical Illusion. AAAS Science Books 11:31 (1975).

  7. Loughman, W.D.: Review of Mertens, T.R., Human Genetics: Readings on the Implications of Genetic Engineering. AAAS Science Books 11:135 (1975).

  8. Loughman, W.D.: Review of Kelly, M.G. and J.C. McGrath, Biology: Evolution and Adaptation to the Environment. AAAS Science Books 11:137 (1975).

  9. Loughman, W.D.: Review of Loehlin, J.C., et al, Race Differences in Intelligence. AAAS Science Books 12:127 (1975).

  10. Loughman, W.D.: Review of Hoagland, M.B., The Roots of Life. A Layman's Guide to Genes, Evolution, and the Ways of Cells. AAAS Science Books 14:160 (1978).

  11. Loughman, W.D.: Review of Barrett, P.H., The Collected Papers of Charles Darwin. AAAS Science Books 13:207 (1978).

  12. Loughman, W.D.: Review of Swanson, C.P., T. Merz, and W.J. Young, Cytogenetics: The Chromosome in Division, Inheritance, and Evolution, 2nd ed. AAAS Science Books 17(1):18 (1981).

  13. Loughman, W.D.: Review of Turner, G.L'E., Collecting Microscopes. AAAS Science Books 17(4):209 (1982).

  14. Loughman, W.D.: Review of Stebbins, G.L., Darwin to DNA, Molecules and Humanity. AAAS Science Books 18(2):77 (1982).

  15. Loughman, W.D.: Review of Angela, Piero and Alberto, The Extraordinary Story of Human Origins. Science Books & Films. December 1993.

  16. Loughman, W.D.: Review of Lauber, Patricia, What Do You See & How Do You See It? Exploring Light, Color, and Vision. Science Books & Films. May, 1995.

  17. Loughman, W.D.: Review of Cavalli-Sforza, Luigi Luca, and Francesco Cavalli-Sforza, The Great Guman Diasporas: The History of Diversity and Evolution. Science Books & Films. Jan./Feb. 1996.

  18. Loughman, W.D.: Review of Zahavi, Amotz and Avishag, The Handicap Principle. Science Books & Films. March 1998.

  19. Loughman, W.D.: Review of Appleyard, Bryan. Brave New Worlds: Staying Human in the Genetic Future. Science Books & Films. Jan./Feb. 1999.

  20. Loughman, W.D.: Review of Dalton, Stephen, Secret Worlds: Photographs by Stephen Dalton. Science Books & Films. July/Aug. 2000.

  21. Loughman, W.D.: Review of Larson, Edward J., Evolution's Workshop: God and Science on The Galapagos Islands. Science Books & Films [pending] (2001).

  22. Loughman, W.D.: Review of Bruce, Jim. Mammals. Science Books & Films [pending] (2002).


Conference presentations (unpublished):

  1. 1983 California Association for Medical Laboratory Technology, 44th Annual Meeting, Oakland, CA. Paper: Loughman, W.D., "Cytogenetics: A New Laboratory Science."

  2. 1981 RAMIS Coordinator's Roundtable, Philadelphia, PA. Paper: Loughman, W.D. and J.Jurrens, "Microcomputers as 'Front Ends' for RAMIS."

  3. 1980 University of Missouri, Columbia. Seminar in Medical Genetics. Paper: Loughman, W.D., "Operational Problems in a Large Cytogenetics Laboratory."

  4. 1980 University of Missouri, Columbia. Seminar in Information Science. Paper: Loughman, W.D., "Building of GENFILES, an Information Network in Medical Genetics."

  5. 1980 Sixth Illinois Conference on Medical Information Systems, Urbana, IL. Paper: Mitchell, J.A., W.D. Loughman, and C.J. Epstein, "GENFILES: An Information Network in Medical Genetics."

  6. 1979 IBM Computer Users Group, ("SHARE") San Francisco, CA. Panelist: "Uses of Data Base Management Systems."

  7. 1978 Department of Biochemistry Seminars, San Francisco State University, San Francisco, CA. Paper: Loughman, W.D., "Cellular Aspects of Fanconi's Anemia."

  8. 1978 Forum West (RAMIS Users Group), Los Angeles, CA. Paper: Loughman, W.D., and D.C. Mosher, "RAMIS for Medical Applications."

  9. 1978 Third Annual Meeting, Association of Cytogenetics Technologists, San Francisco, CA. Moderator: "Clinical Open Forum."

  10. 1978 29th Annual Meeting, American Society of Human Genetics, Vancouver, B.C., Canada. Paper: Loughman, W.D. and D.C. Mosher, "A New Computerized Medical Genetics Data Management System." -and- Invited Panelist: Workshop on Pre-Natal Detection of Mosaicism.

  11. 1977 Research Medicine Grand Rounds, Donner Laboratory, Univ. Calif., Berkeley. Paper: Loughman, W.D., "Prenatal Cytogenetic Diagnosis."

  12. 1977 Workshop on Cytogenetic Laboratory Certification and Licensing, Albany, NY.Observer for California State Department of Health.

  13. 1974 Biomedical Division Seminar, Lawrence Livermore Laboratory, Livermore, CA. Paper: Loughman, W.D., "Cytogenetics and Fanconi's Anemia."

  14. 1973 XIIIth International Congress of Genetics, Berkeley, CA. Paper: Loughman, W.D., "Fanconi's Anemia: Intra-Family Variation in Radio-Thymidine Labelling Patterns of Cultured Lymphocyte Metaphases."

  15. 1973 Biological Sciences Research Center Special Seminar, Univ. North Carolina, Chapel Hill, NC. Paper: Loughman, W.D., "Cytogenetics and Fanconi's Anemia."

  16. 1971 18th Ann ual Meeting of the Society of Nuclear Medicine, Los Angeles, CA. Paper: Fawwaz, R.A., P. Sanchez, W. Loughman, L. Ross, and B. Shipley, "The Distribution of Intravenously Administered 63Ni-Protoporphyrin in Canine Lymph Nodes."

  17. 1970 Special Meeting of Directors and Department Heads, Lawrence Radiation Laboratory, Livermore, CA. Paper: Loughman, W.D., "Radiation-Induced Genetic Change in Humans: Some Current Concepts."

  18. 1969 Department of Genetics, Univ. California, Berkeley, CA. Paper: Loughman, W.D., "Genetic Effects of LSD Compared to Those of Innocuous Drugs".

  19. 1968 Pion Advisory Committee, United States Atomic Energy Commission, Washington, DC. Paper: Loughman, W.D., "RBE of Negative Pions."

  20. 1967 Society of Nuclear Medicine, Annual Meeting, Seattle, Washington. Paper: Loughman, W.D., "RBE of Negative Pion Beams."

  21. 1967 First International Symposium on Biological Interpretation of Dose from Accelerator Produced Radiation, Berkeley, CA. Paper: Feola, J.M., W.D. Loughman and S.P. Richman, "Pion Radiobiology."

  22. 1966 Third International Conference on Radiation Protection, Cortina, Italy. Paper: Curtis, S.B., J.M. Feola, W.D. Loughman, M.R. Raju, C. Richman, and J.H. Lawrence, "Present Prospects of Pion Radiotherapy"

  23. 1965 Society for Experimental Biology and Medicine, Pacific Coast Section, San Francisco, CA. Paper: Aceto, H. and W.D. Loughman, "Preliminary Physical and Biological Experiments with Negative Pi-Mesons."

  24. 1964 Xth Congress of the International Society of Hematology, Stockholm, Sweden. Paper: Winchell, H.S., M. Pollycove, W.D. Loughman, V. Richards, L. Kim and J.H.

Publication Summary:

     Seventy-six publications, twenty-four conference presentations, and contributions to six biology texts, represent research in radiochemistry, immunosuppression, transplantation, radiobiology, mutagenicity, neoplasia, human genetics, cytogenetics, pre-natal diagnosis, and computer science.


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