This tall, thin 36 y/o male presented to the ER with chest pain. Selected images from his chest CT with contrast shown above demonstrate aneurysmal dilatation of the ascending aorta. Combined with the history this suggests Marfan's syndrome which was indeed the clinical diagnosis.

  1. von Kodolitsch Y, Simic O, Nienaber CA. Aneurysms of the ascending aorta: diagnostic features and prognosis in patients with Marfan's syndrome versus hypertension. Clin Cardiol 1998 Nov;21(11):817-24 UI:99042635
  2. de Virgilio C, Cherry KJ Jr, Schaff HV. Multiple aneurysms and aortic dissection: an unusual manifestation of Marfan's syndrome. Ann Vasc Surg 1994 Jul;8(4):383-6 UI:95034020
  3. Furthmayr H, Francke U. Ascending aortic aneurysm with or without features of Marfan syndrome and other fibrillinopathies: new insights. Semin Thorac Cardiovasc Surg 1997 Jul;9(3):191-205 UI:97408820
  4. LeMaire SA, Coselli JS. Aortic root surgery in Marfan syndrome: current practice and evolving techniques. J Card Surg 1997 Mar-Apr;12(2 Suppl):137-41 UI:97417667
  5. Child AH. Marfan syndrome--current medical and genetic knowledge: how to treat and when. J Card Surg 1997 Mar-Apr;12(2 Suppl):131-5; discussion 135-6 UI:97417666
  6. Wieczorek P, Riegel MB, Quattro L, DeMaio K. Marfan's syndrome and surgical repair of ascending aortic aneurysms. AORN J 1996 Dec;64(6):895-913; quiz 916-8, 921-2 UI:97120008
  7. Hayashi J, Moro H, Namura O, Yagi N, Ohzeki H, Watanabe H, Miyamura H, Eguchi S, Kimura M. Surgical implication of aortic dissection on long-term outcome in Marfan patients. Surg Today 1996;26(12):980-4 UI:97170655
  8. Mohr R, Adar R, Rubinstein Z. Multiple aortic aneurysms in Marfan's syndrome. Case report and review of the literature. J Cardiovasc Surg (Torino) 1984 Nov-Dec;25(6):566-70 UI:85080197
  9. Svensson LG, Labib SB, Eisenhauer AC, Butterly JR. Intimal tear without hematoma: an important variant of aortic dissection that can elude current imaging techniques. Circulation 1999 Mar 16;99(10):1331-6 UI:99177128
  10. Hayward C, Brock DJ. Fibrillin-1 mutations in Marfan syndrome and other type-1 fibrillinopathies. Hum Mutat 1997;10(6):415-23 UI:98062175

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