This 36 y/o male patient with minimally elevated calcium and mildly elevated parathormone level was referred for radioisotope parathyroid imaging. Images from the Tc99m sestamibi scan are shown above. A parathyroid adenoma in the lower pole of the right lobe of the thyroid was suspected and the patient underwent surgical exploration. Frozen sections at the time of surgery showed a papillary carcinoma of the thyroid. Examination of the thyroidectomy specimen demonstrated a focal 1 cm. papillary carcinoma of the thyroid in the right lower pole with foci of papillary carcinoma seen in other sections of the thyroid. Post operatively the parathormone levels have remained elevated and further evaluation to search for the parathyroid adenoma is planned.

  1. Roelants V, Beckers C. 99mTc-MIBI in differentiated thyroid carcinoma. J Nucl Med 1999 Oct;40(10):1769 UI:99449031
  2. Grunwald F, Menzel C, Bender H, Palmedo H, Willkomm P, Ruhlmann J, Franckson T, Biersack HJ. Comparison of 18FDG-PET with 131iodine and 99mTc-sestamibi scintigraphy in differentiated thyroid cancer. Thyroid 1997 Jun;7(3):327-35 UI:97369758
  3. Miyamoto S, Kasagi K, Misaki T, Alam MS, Konishi J. Evaluation of technetium-99m-MIBI scintigraphy in metastatic differentiated thyroid carcinoma. J Nucl Med 1997 Mar;38(3):352-6 UI:97228438
  4. Learoyd DL, Roach PJ, Briggs GM, Delbridge LW, Wilmshurst EG, Robinson BG. Technetium-99m-sestamibi scanning in recurrent medullary thyroid carcinoma. J Nucl Med 1997 Feb;38(2):227-30 UI:97178349
  5. Cavalieri RR. Nuclear imaging in the management of thyroid carcinoma. Thyroid 1996 Oct;6(5):485-92 UI:97090789
  6. Alper E, Akbunar T, Tamgac F. Visualization of papillary thyroid carcinoma and its metastatic lymph nodes. Images with Tc-99m pertechnetate, Tl-201, and Tc-99m sestamibi. Clin Nucl Med 1996 Oct;21(10):815-6 UI:97052303
  7. Lee J, Cutrone JA, Marcus CS. Tc-99m sestamibi and In-111 pentetreotide uptake in metastatic papillary thyroid carcinoma. Clin Nucl Med 1995 Oct;20(10):867-8 UI:96114214
  8. Kosuda S, Yokoyama H, Katayama M, Yokokawa T, Kusano S, Yamamoto O. Technetium-99m tetrofosmin and technetium-99m sestamibi imaging of multiple metastases from differentiated thyroid carcinoma. Eur J Nucl Med 1995 Oct;22(10):1218-20 UI:961199
  9. Dworkin HJ, Meier DA, Kaplan M. Advances in the management of patients with thyroid disease. Semin Nucl Med 1995 Jul;25(3):205-20 UI:96024161

Use the Back or Backward button on your browser to return