Occurs at a frequency of 1/1,000 female live births. No specific abnormalities are usually associated with this condition. The vast majority of women who have this condition are normal mentally and physically and are fertile. Most women with XXX who are fertile do not tend to pass the extra X to their offspring. This extra X chromosome tends to end up in a polar body after the first meiosis division. It is also possible to inherit 4 or 5 Xs. With each extra X there tends to be a corresponding increase in mental handicap, a chance of being sterile, and a lack of secondary sex characteristics.