Classification of Chromosomes for Karyotyping

Chromosomes are arranged into seven groups based on size and centromere location. The centromeres can be found in the middle of the chromosome (median), near one end (acrocentric), or in between these first two (submedian)

Group A: chromosomes 1-3 are largest with median centromere.

Group B: chromosomes 4-5 are large with submedian centromere

Group C: chromosomes 6-12 are medium sized with submedian centromere

Group D: chromosomes 13-15 are medium sized with acrocentric centromere

Group E: chromosomes 16-18 are short with median or submedian centromere

Group F: chromosomes 19-20 are short with median centromere

Group G: chromosomes 21-22 are very short with acrocentric centromere.

Chromosome X is similar to group C.

Chromosome Y is similar to group G

Return to the Karyotype index