Amtrak Trains 21 & 22, Texas Eagle

Tower 105 to Centex, Track 1

Tower 112 to Centex, Track 2

Centex to Taylor

Taylor to Temple

Temple to Fort Worth

Fort Worth to Dallas

DFW Junction to Ennis Junction

Ennis Junction to KCS Junction

KCS Junction to Big Sandy

Big Sandy to Longview

Longview to Marshall

Marshall to Texarkana

Texarkana to Hope

Hope to Gurdon

Gurdon to Little Rock

Little Rock to North Little Rock

North Little Rock to Bald Knob

Bald Knob to Poplar Bluff

Poplar Bluff to St. Louis (Iron Mountain Junction)

Iron Mountain Junction to Grand Avenue

Grand Avenue to Gratiot

Until the mid 2000s, Amtrak trains on the St. Louis-Chicago route used the Merchants Bridge line between Gratiot and WR Tower

Gratiot to Bremen

Bremen to SH Interlocking

SH Interlocking to WR Tower

Gratiot to Q Tower

Q Tower to WR Tower

WR Tower to Lenox

Lenox to Wood River

Wood River to Godfrey

Godfrey to Springfield

Springfield to Mazonia

Mazonia to Pequot and South Joliet

Pequot to Joliet

Argo to Joliet

Corwith X-ing to Argo

Bridgeport to Corwith X-ing

21st Street to Bridgeport

Chicago Union Station to 21st Street and Halsted Street