delta storage pool deficiency

what is delta spd

 

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Selected Medical Research Papers about Delta SPD from 1996 to 2004 (links to PubMed):

The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage. Blood. 2004 Dec 1;104(12):3603-10. Epub 2004 Aug 05.

Molecular defects that affect platelet dense granules. Semin Thromb Hemost. 2004 Oct;30(5):537-47. (Note: This article was written by the doctors involved in the NIH studies.)

Management of platelet storage pool deficiency during pregnancy. Aust N Z J Obstet Gynaecol. 2003 Apr;43(2):171-2.

Phosphotyrosine proteins in platelets from patients with storage pool disease: direct relation between granule defects and defective signal transduction. Haematologica. 2002 Jun;87(6):629-36.

Platelet storage pool deficiency of alpha and delta granules. Arch Pathol Lab Med. 2001 Aug;125(8):1125-6.

Delta-storage pool disease in infancy with absence of blood serotonin associated with psychomotor retardation. Pediatr Hematol Oncol. 2001 Jul-Aug;18(5):355-7.

Acquired delta-storage pool deficiency associated with idiopathic myelofibrosis. Leuk Lymphoma. 2000 May;37(5-6):623-7.

Platelet ultrastructural morphometry for diagnosis of partial delta-storage pool disease in patients with mild platelet dysfunction and/or thrombocytopenia of unknown origin. A study of 24 cases. Haematologica. 2000 Jun;85(6):619-26.

Evaluation of platelet function with the PFA-100 system in patients with congenital defects of platelet secretion. Thromb Res. 1999 Nov 1;96(3):213-7.

Correction of the platelet adhesion defect in delta-storage pool deficiency at elevated hematocrit--possible role of adenosine diphosphate. Blood. 1996 May 15;87(10):4214-22.

 

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Updated 08-Apr-2009
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