Genetic Engineering Toolbox

Gel Electrophoresis



Description and Procedure:

Gel electrophoresis separates restriction fragments of DNA by length resulting in a unique arrangement of bands. An electric field causes negatively charged DNA fragments to move through a gel of tangled polymer filaments. The smaller the DNA fragment the faster it will move through the gel towards the positive end.

Uses or Function:

Used to separate DNA fragments so they can be isolated and identified. The pattern produced may be used in law or biology to show how closely two samples are related. The pattern produced is often called a DNA fingerprint. What is DNA Fingerprinting?


See autoradiography & PCR