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Donepezil (Aricept) CADASIL Study    
CTWHH was honored in recruiting patients for this study.  Potential patients are notified directly by CTWHH.  It will be their decision to contact the study  Coordinator if they are interesting in participating in the study. 

The study opened January 2006   
Closed July 2006

CTWHH was contacted by Eisai/Pflizer to place this CADASIL Study on the web page and contacted patients to inform them of the study.

Results Of This Study

http://clinicaltrials.gov/ct2/show/NCT00103948

This was a randomized trial of Donepezil (Aricept, Eisai/Pfizer) in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts
and leukoencephalopathy (CADASIL). 

CTWHH was honored to have been contacted by Eisai/Pfizer to recruit patients for this study. We notified patients to directly contact a researcher
to participate in the study.  No personal information was shared as we respect your privacy.

Thank you to everyone who was screened and participated in the study. Over 255 patients were screened worldwide to participate in the study;
approximately 168 patients  have completed the study. We want to personally want to thank the Eisai and Parexel Companies,  the doctors
as well as the researchers for their dedication and hard work.

Dr. Edwin H. Kolodny, New York
Dr. Gregory Pastores, New York
  Dr. Michael D. Hill, Alberta, Calgary , Canada
Professor Antonio Federico,  Siena, Italy
Dr. Jose Biller, Loyola University Maywood, IL   Dr. Keith Muir, Glasgow, Scotland, UK
Dr. Stephen Salloway, Providence,  Rhode Island Professor Hugh Markus, London, England
Dr. James W. Schmidely, University of Arkansas Dr. Martin Dichgans, Marchionistrasse München Germany
Dr. Michael Geschwind, San Francisco, California  

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