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CADASIL is an inherited form of stroke and other impairments. This condition affects small blood vessels, mainly in the brain. An abnormality in the muscle cells surrounding these blood vessels (vascular smooth muscle cells) gradually destroys the blood vessel cells. The resulting blood vessel damage can lead to migraines, emotional and mental disorders, stroke-like episodes, dementia, and other impairments of normal brain function. Patients with CADASIL are also at increased risk of heart attack (myocardial infarction) because of damaged blood vessels in the heart. Most patients with CADASIL do not have the common risk factors for stroke and heart attack, such as high blood pressure and high cholesterol, although in some cases these features may also be present.  (http://ghr.nlm.nih.gov/condition=cadasil)  

Within this site, you will find information about characteristics associated with CADASIL and be able to educate yourself, families’ members and the medical community.  Information about the CADASIL REGISTRY, most recent research, newsletters, pending conference, doctor locator and links to other sites of interest are also contained inside this website.