Isaac Abercrombie (?-1825) purchased 100 acres of land on a branch of “Reburns Creek” -- an area that became Laurens County, South Carolina -- from John Copland on 2 August 1769. John Copland had petitioned for the land on 22 June 1767 “on the bounty” -- a provision for foreign immigrants. It was surveyed on 1 October 1767 by deputy surveyor Pat. Calhoun, certified on 23 February 1768 and was granted in 1768.

On 8 June 1761 at St. Nicholas Church of Scotland, Aberdeen, Scotland, John Copland, merchant, married Isobel Abercrombie, daughter of the deceased Rev. Robert Abercrombie, minister at Leslie, Scotland. John and Isobel had a daughter, Margaret Copland, who was baptized at St. Nicholas on 17 April 1762. No other children of John Copland and Isobel Abercrombie are recorded in the baptism registers for Britain, but it is unknown if this was the same John Copland who sold land to Isaac Abercrombie in South Carolina in 1769.

On 8 November 1795 Isaac Abercrombie, freeholder of Anson County, North Carolina, sold this Laurens County land to James Abercrombie. And on 22 February 1798 James Abercrombie sold it to Anderson Arnold with his wife, Ann Abercrombie, renouncing her dower.

On 18 August 1789 Isaac Abercrombie purchased land in Anson County, North Carolina.

Isaac Abercrombie lived in Anson County, North Carolina from at least 1790 to 1820 because he appears there in every federal census during that time.

In the 1800 census for Anson County "Isaac Abercromby" had a household consisting of one male over 45 years of age [himself], one male 16-26, one male 10-16, three males under 10, one female 26-45, one female 10-16, one female under 10 and three slaves.

After 1820 Isaac moved with his adult children to Perry County, Alabama and left a will there, dated 10 June 1824, proved 5 August 1825. Isaac’s will named his wife, Mary, sons: Archibald Abercrombie, James Abercrombie, Isaac Abercrombie, Alexander Abercrombie, Thomas Abercrombie, and daughters: Mary Burroughs [wife of William Burroughs], and Elizabeth Billingsley, deceased wife of Thomas Billingsley.