Research
through Genetics
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HAM
DNA Project |
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Results
from the HAM Surname DNA Project:
The
results from the HAM Surname DNA Project will be posted to the Family
Tree DNA web site for the HAM DNA
Project, and analyzed here.
The analysis here will be to cross-reference the DNA sequences with the
oldest known ancestor.
HAM
DNA Phylogenetic
charts of this data.
HAM DNA "CLICK" genetic study (PDF).
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The markers in RED have shown a
faster mutation rate then the average, and therefore these markers are
very helpful at splitting lineages into sub sets, or branches, within
your family tree. The volatility rate of these markers has not been
established.
Explained another way, if you match exactly on all of the markers
except for one or a few of the markers we have determined to mutate
more quickly, then despite the mutation, this mismatch only slightly
decreases the probability of two people in your surname group who match
11/12 or even 23/25 of not sharing a recent common ancestor.
If you have 2 people who match, exactly, except on a single marker and that marker is one that is highlighted in RED within your surname group then the current estimate of distance between 2 people are related is probably overstated, and they are more closely related than could be assumed by the distance suggested by a standard single marker deviation.
A
comprehensive evaluation of marker by marker volatility rates is
currently being organized by the Molecular Lab for Science and
Evolution at the University of Arizona and FTDNA surname groups with
verified documented genealogies will be able to participate in this
study which began during August 2003.
NOTES:
DYS 464a-d is a highly volatile marker, and
must be analyzed carefully, following the guidelines set forth by the
folks at the Lab for Molecular Science and Evolution at the University
of Arizona.
YCA II a/b are the only markers in
our system that uses a bi (2) base pair repeat motif. In simple terms
this means that a move by 1 or 4 'repeats' will be counted as a single
evolutionary event rather then 4 evolutionary events when calculating
genetic distance.
DYS 389ii and the DYS 389i calculation that is done
funny. They are considered to be a pair.
You are supposed to subtract the differences between 389ii
and 389i for each person, then compare the two people.
Something like this:
40777:
DYS389ii - DYS389i = 30 - 14 = 16
42370: DYS389ii -
DYS389i = 29 - 13 = 16
and 16 - 16 =
0 (which means no difference)
Then, subtract them from each of our values (down the
column) for DYS389i (ONLY):
40777 ( DYS389i ): 14
42370 ( DYS389i ): 13
---
1 so there is one mutation for both 389i and
389ii
and we have +
1 mutation at DYS19
between 40777 and 42370.
----
so
2 total mutations
between participants 40777 and 42370
That is, 40777 and 42370 are only off by 2 markers out of the first 25 markers
I
had to look this up at the FTDNA Group Administrator page. I
would cut and paste here, but they say this is also explained on the
web page for Kevin Duerinck:
http://www.duerinck.com/results.html